NEWS and ARTICLES
BBC News (UK) - Oxford trust
publishes alcohol-related foetus disorder guidelines
A charity has
published recommendations for medical staff to tackle a foetal
disorder caused by drinking alcohol during pregnancy.
Science Daily - Signaling Pathway
Linked to Fetal Alcohol Risk: Molecular Switch Promises New Targets
for Diagnosis and Therapy
Fetal alcohol
syndrome is the leading preventable cause of developmental disorders
in developed countries. And fetal alcohol spectrum disorder (FASD), a
range of alcohol-related birth defects that includes fetal alcohol
syndrome, is thought to affect as many as 1 in 100 children born in
the United States.
Memphis Commercial
Appeal (USA) - Alcohol, pregnancy add up to tragedy
The term fetal
alcohol syndrome (FAS) refers to the most severe permanent effects of
a child's exposure to alcohol while in the mother's womb, including
mental retardation, abnormal physical appearance and behavior, and
extreme limitation of normal lifetime capabilities.
Memphis Commercial
Appeal - It happens: women accidentally drink alcohol unaware
they're pregnant
Many women know
that alcohol can be harmful to an unborn baby and they plan to
abstain once they're pregnant. Sometimes, however, a woman drinks
alcohol before she knows she's pregnant and then is afraid of the
ramifications.
Iowa Now (USA) -
UI team to study alcohol's effects on unborn babies
A University of
Iowa research team has been awarded nearly $2 million to study the
effects on unborn babies from mothers who abuse alcohol during
pregnancy.
CJOB
(France/Canada) - French Group Learning First-Hand about FASD
A nine-person
delegation from France arrives in Winnipeg Thursday to learn about
Manitoba's innovative programs for the diagnosis, prevention and
treatment of Fetal Alcohol Spectrum Disorder (FASD).
The Canberra Times
(Australia) - Pregnant pause needed for alcohol awareness
It's not the
doctor's fault, really. Attention deficit hyperactivity disorder has
become quite an acceptable label to paste on children these days.
The Elkhart Truth
- Dog could help Goshen boy with fetal alcohol spectrum disorder
Like many
9-year-olds, Tyler Kidder of Goshen enjoys playing with Lego pieces,
watching “Tom and Jerry” and picking on his younger brother. His
playing time, though, can be interrupted by his bouts of extreme
anger, name-calling and emotional meltdowns.
Yukon News - A
life of misunderstandings
Donna Debolt says
that of all the disabilities she is aware of, fetal alcohol spectrum
disorder is the most misunderstood.
SPECIAL
INFORMATION
The Swedish
FAS-förening and Malmö Högskola will start a small research
project about children with FASD. The primary focus will be on
everyday life in the family (and what kind of support there is in the
society). The FAS-förening would like to hear about similar
research that has been done with this focus around the world. Contact
Katarina Wittgard at FAS@telia.com.
MATERIALS and
VIDEOS
Murkowski's Advancing FASD Research,
Prevention & Services Act
OBG Management –
Alcohol: An unfortunate teratogen
Medical students
learn early in their education that alcohol is a teratogen. Despite
this widespread knowledge, many obstetricians counsel patients about
the safety of low doses of alcohol in pregnancy.
RESEARCH
Journal of
Population Terapeuthics - Fetal Alcohol Spectrum Disorders:
Knowledge and Screening Practices of University Hospital Medical
Students and Residents
A new study has
recently been published with the purpose of evaluating the knowledge
and screening practices of pre-clinical medical students and clinical
providers on FAS, FASD, and alcohol consumption.
NIH - Scientists
identify molecular events that underlie FASD
Scientists have
identified a molecular signaling pathway that plays an important role
in the development of fetal alcohol spectrum disorders (FASD). The
new research in cells and mice, supported by the National Institute
on Alcohol Abuse and Alcoholism (NIAAA), part of the National
Institutes of Health, points to candidate genes for FASD
susceptibility and may open new avenues for developing drugs to
prevent alcohol damage to the fetal brain.
Addiction - A
randomized controlled trial of motivational interviewing to prevent
risk for an alcohol-exposed pregnancy in the Western Cape, South
Africa
A five-session
motivational interviewing intervention was found to be effective with
women at risk of an alcohol-exposed pregnancy, and could be
implemented as part of routine primary care clinic services in
similar populations. The message of ‘no alcohol in pregnancy’
should be adapted to include better family planning and early
recognition of pregnancy.
PNAS -
Mitogen-activated protein kinase modulates ethanol inhibition of
cell adhesion mediated by the L1 neural cell adhesion molecule
There is a genetic
contribution to fetal alcohol spectrum disorders (FASD), but the
identification of candidate genes has been elusive.
Genetics and
Molecular Biology - Maternal drinking behavior and Fetal Alcohol
Spectrum Disorders in adolescents with criminal behavior in southern
Brazil
Prenatal alcohol
exposure can have serious and permanent adverse effects. The
developing brain is the most vulnerable organ to the insults of
prenatal alcohol exposure. A behavioral phenotype of prenatal alcohol
exposure including conduct disorders is also described.
Alcoholism - Does
Binge Drinking During Early Pregnancy Increase the Risk of
Psychomotor Deficits?
The potential
effects of binge drinking during pregnancy on child motor function
have only been assessed in a few, small studies. We aimed to examine
the effects of binge alcohol consumption during early pregnancy,
including number of binge episodes and timing of binge drinking, on
child motor function at age 5.
Alcoholism -
Gestational Choline Supplementation Normalized Fetal
Alcohol-Induced Alterations in Histone Modifications, DNA
Methylation, and Proopiomelanocortin (POMC) Gene Expression in
β-Endorphin-Producing POMC Neurons of the Hypothalamus
Prenatal exposure
to ethanol (EtOH) reduces the expression of hypothalamic
proopiomelanocortin (POMC) gene, known to control various
physiological functions including the organismal stress response. In
this study, we determined whether the changes in POMC neuronal
functions are associated with altered expressions of
histone-modifying and DNA-methylating enzymes in POMC-producing
neurons, because these enzymes are known to be involved in regulation
of gene expression. In addition, we tested whether gestational
choline supplementation prevents the adverse effects of EtOH on these
neurons.
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