Monday, March 23, 2020

FASD News - 11/2020

Genetic Engineering & Biotechnology News - Scorpion Venom May Serve as Novel Therapy for Fetal Alcohol Spectrum Disorder
Scientists led by the Children’s National Hospital faculty were able to “rescue” a preclinical model of fetal alcohol spectrum disorder (FASD) in juvenile models, reversing motor skill deficits with the help of a novel drug derived from scorpion venom.
Anishinabek News (Canada) - Changing the language around FASD will help people live with their strengths and challenges
Victim. Villain. A lifelong sentence. These are words and negative perceptions that people working in the field of Fetal Alcohol Spectrum Disorder (FASD) are trying to dispel from the complex conversation around the brain-based, lifelong physical disability.
The Conversation AU (Australia) - Alcohol warning labels need to inform women of the true harms of drinking during pregnancy
Federal and state ministers will meet tomorrow to decide whether to compel alcohol manufacturers to include clear labels on all alcohol products that warn against the harms of drinking while pregnant.
The Sydney Morning Herald (Australia) - Yes, ministers, warning labels will save women and their unborn children from alcohol harm
Each week in my assessment clinic for fetal alcohol spectrum disorder I see children struggling with learning, behaviour and development, with physical disability and intellectual impairment – the result of a brain injury caused by prenatal exposure to alcohol.
CafeMom - Husband Gets Slammed Online for Refusing To Buy Wine for His Pregnant Wife
For one couple this debate isn't just a hypothetical. Taking to Reddit this week, a dad-to-be explained how he recently refused to pick up wine for his very pregnant wife, for fear it might harm their baby -- even though she felt like one little sip wouldn't do any harm.
The Sydney Morning Herald (Australia) - Alcohol labelling: Poll shows many still in dark over risk during pregnancy
If health experts win ministerial support on Friday, all alcoholic drinks will carry red and black labels, saying "health warning" and showing a pregnant woman in silhouette lifting a wine glass to her mouth.
Wellington Faculty of Science - A disorder falling through the cracks
Foetal Alcohol Spectrum Disorder is all too common, particularly among young people who end up in the criminal justice system, so why is there so little support for people suffering from it, asks Te Herenga Waka—Victoria University of Wellington's Dr Dougal Sutherland.
University of Auckland (New Zealand) - Courts no place for fetal alcohol victims
People with fetal alcohol syndrome are still being punished by the criminal justice system, despite the Teina Pora case, writes MBChB student Emma Espiner.

UW Medicine - Finding a Treatment for Fetal Alcohol Spectrum Disorder
When developing fetuses are exposed to alcohol, they are at risk for a variety of irreversible birth defects, and it seems that any amount of alcohol could lead to fetal alcohol spectrum disorder (FASD).
The WHOot - How Alcohol Affects Unborn Babies
The dangers of Alcohol are becoming more pronounced by the day. Drinking has become a National sport and addiction is all too real.
Bethany Christian Services - Parenting a Child with Fetal Alcohol Syndrome
NOFAS-UK - Stay-at-Home-Guide for Kids with FASD
Young people with FASD can help plan for days when they may need to be at home. This guide offers some suggestions – but it’s only a start to help get everyone thinking of some fun and calming home activities.
The FASD Success Show - Dr. Ira Chasnoff Talks FASD and The Online World
Meet Dr. Ira J. Chasnoff. In this episode, we speak with Dr. Chasnoff about his work and his book: FASD and the Online World, a hot topic for many caregivers.
The FASD Success Show - Elizabeth Anne Russell Helping Birth Moms Heal
Meet Elizabeth (Anne) Russell. She is the founder of The Russell Family Fetal Alcohol Spectrum Disorders Association. Anne is also the birth mother of two individuals with Fetal Alcohol Spectrum disorder(FASD).

Canadian Journal of Community Mental Health - A Qualitative Investigation into Barriers and Enablers for the Development of a Clinical Pathway for Individuals Living with FASD and Mental Disorder/Addictions
It is common for individuals with fetal alcohol spectrum disorders (FASD) to require support for mental health and addictions but there are challenges associated with receiving appropriate care in Canada.
Alcohol - Proceedings of the 2019 Annual Meeting of the Fetal Alcohol Spectrum Disorders Study Group.
The 2019 Fetal Alcohol Spectrum Disorders Study Group (FASDSG) meeting was entitled "Computational Approaches to Studying Behavioral Control and Individual Change."
Alcohol Clin Exp Res - Characterizing Alcohol-Related Neurodevelopmental Disorder (ARND): Prenatal Alcohol Exposure and the Spectrum of Outcomes.
ARND has been a subject of debate. This analysis suggests effects of alcohol on behavior and cognition even in the absence of the characteristic facial features and growth deficiency that can be identified.
Nature Neuroscience - Kcnn2 blockade reverses learning deficits in a mouse model of fetal alcohol spectrum disorders
Pharmacologic blockade of Kcnn2 improves these learning deficits, suggesting Kcnn2 blockers as a new intervention for learning disabilities in FASD.
bioRxiv - Increased Ethanol Intake is Associated with Social Anxiety in Offspring Exposed to Ethanol on Gestational Day 12
Taken together, these data indicate that PAE differentially affects the interactions between social anxiety, ethanol intake, and drinking context in males and females. These findings extend our understanding of the complexity and persistence of PAE’s sex-dependent effects into adulthood.
International Journal of Neuropsychopharmacology - Postnatal Ethanol Exposure Activates HDAC-Mediated Histone Deacetylation, Impairs Synaptic Plasticity Gene Expression and Behavior in Mice
These findings demonstrate that CB1R/HDAC-mediated epigenetic remodeling disrupts gene expression and is a critical step in FASD-associated cognitive decline but is reversed by restoration of histone acetylation in the brain.
Journal of Neurodevelopmental Disorders - Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder
These data support choline as a potential neurodevelopmental intervention for FASD and highlight the need for long-term follow-up to capture treatment effects on neurodevelopmental trajectories.
Journal of Pediatric Urology - Incontinence in persons with Fetal Alcohol Spectrum Disorders (FASD): a Polish cohort
Children and adolescents with FAS, pFAS, ARND, GKA, and GKG are affected by incontinence. Highest rates were observed in pFAS and ARND. Persons with FAS were mostly affected by DUI, pFAS by NE, and ARND by FI.
NeuroToxicology - Fetal alcohol spectrum disorders model alters the functionality of glutamatergic neurotransmission in adult zebrafish
Fetal alcohol spectrum disorders (FASD) describe a wide range of ethanol-induced developmental disabilities, including craniofacial dysmorphology, and neurochemical and behavioral impairments.
Addiction - Alcohol use in pregnancy and its impact on the mother and child
This review discusses the history, epidemiology and clinical presentations of prenatal alcohol exposure, focusing on FASD and FAS, and the impact of evidence on future research, practice and policy directions.
Journal of law and medicine - Warning Labels about Alcohol Consumption and Pregnancy: Moving from Industry Self-regulation to Law.
Alcohol consumption during pregnancy carries known risks to the foetus in the form of foetal alcohol spectrum disorder (FASD). One of the interventions for the prevention of FASD is the application of warning labels to packaged alcoholic beverages.
Alcohol consumption in pregnant women was higher than the estimated for most Latin- American countries, and of the considered characteristics, was almost exclusively related to consumption patterns before pregnancy.
Addictive Behaviors - Changes in alcohol use and heavy episodic drinking in U.S. women of childbearing-age and peripartum between 2001-2002 and 2012-2013
Alcohol use and HED increased in last 10 years in both childbearing age and pregnant and postpartum US women. That questions the impact of implemented laws, policies and alcohol guidelines in this population within the last 10 years.
Reproductive Biology and Endocrinology - Smoke, alcohol and drug addiction and female fertility
Currently, the most consistent evidences of a detrimental effect of smoke, alcohol and addictive drugs on specific domains of the female reproductive function are provided by experimental studies in animals.
Nordic Studies on Alcohol and Drugs - Maternal alcohol intakes before and during pregnancy: Impact on the mother and infant outcome to 18 months
Maternal alcohol consumption exceeding 50 g per session both before and during pregnancy was associated with decreasing vocal ability in the 18-month old infant.
Pediatric Research - Drinking at the end of pregnancy: why don’t we see it?
Prenatal alcohol exposure in late pregnancy is rarely studied and this makes the contribution by Umer et al. very useful.1 Their study adds to the accumulating data demonstrating that screening dried blood spots can identify biomarkers of prenatal alcohol exposure at the end of pregnancy, which may be more common than previously thought.

Rynek Zdrowia (Poland) - Badania: odkrycie leku na problemy neurorozwojowe wywołane przez FASD
Lek powstały z jadu skorpiona eliminuje opóźnienia w rozwoju motorycznym u myszy ze Spektrum Alkoholowych Uszkodzeń Płodu (FASD) - wynika z badania opublikowanego na łamach czasopisma „Nature Neuroscience”. (Austria) - Diagnose Fetales Alkoholsyndrom: „Wie ein Gewitter im Kopf“
Fetales Alkoholsyndrom. Ingrid kümmert sich um Pflegeenkel Michael, er hat FAS. Es fehlt an adäquater Betreuung
ZARLLOR (Italy) - Álcool na gravidez: o grande perigo para a gestante e o bebé
Gestantes que bebem álcool durante a gravidez colocam em risco o bebé. A criança e os pais precisam lidar com os danos tardios pelo resto das suas vidas.

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